Journal of Craniomaxillofacial Research 2017. 4(2):372-376.

Carcinosarcoma of minor salivary gland of lower lip with pelvic metastasis: A case report
Abbas Karimi, Mahboube Hasheminasab, Samira Derakhshan

Abstract


Carcinosarcoma of salivary gland is a rare and aggressive tumor composed of both carcinomatous and sarcomatous components which metastasize together. Most tumors arise in parotid gland from a preexisting pleomorphic adenoma.
Methods and Results: We report a case of carcinosarcoma of minor salivary gland of lower lip with subsequent infiltration to mandible and pelvic metastasis after recurrence. The patient
was a 38 year old man who underwent surgical resection and adjuvant chemo radiotherapy and demonstrates recurrence after 9 months with metastasis to left iliac fossa.
Conclusion: Carcinosarcoma of minor salivary gland is an extremely rare malignancy with poor prognosis and is best managed by combination of surgical resection and postoperative radiation.
Key words: Carcinosarcoma, Salivary gland, Metastasis, Recurrence.

Keywords


Carcinosarcoma; Salivary gland; Metastasis; Recurrence.

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References


Owaki S, Kitano H, Hanada M, Asada Y, Sugihara H, Moritani S, Banba M. Carcinosarcoma of the submandibular gland: an autopsy case. Auris Nasus Larynx. 2003 Dec;30(4):439-42.

Filho JCG; Carvalho LGM; Pinheiro Junior NF; de Freitas LAR; Athanazio PRF; Athanazio DA. Carcinosarcoma of the parotid gland featuring foci of malignant giant cell tumor. J Bras Patol Med Lab •

Apr 48 (2) :129-134.

Ord RA, Salama AR. Is it necessary to re- sect bone for low grade mucoepidermoid car- cinoma of the palate? Br J Oral Maxillofac Surg. 2012 ec;50(8):712-4.

Pires FR, Pringle GA, de Almeida OP, Chen SY.Intra-oral minor salivary gland tumors: a clinico-pathological study of 546 cases. Oral Oncol. 2007 May; 43(5):463-70.

Kwon MY, Gu M. True malignant mixed tumor (carcinosarcoma) of parotid gland with unusu- al mesenchymal component: a case report and review of the literature. Arch Pathol Lab Med 2001;125:812-5.

Neville BW, Damm DD, Allen CM, Bouquot JE.Oral and maxillofacial pathology. Saunders. 2009,third edition. p 492.

Staffieri C, Marioni G, Ferraro SM, Marino F, Staf- fieri A. Carcinosarcoma de novo of the parotid gland. Oral Surg Oral Med Oral Pathol Oral Ra- diol Endod. 2007 Aug;104 (2):e35-40.

Eveson, J. W. et al. Tumours of the salivary glands.In: Leon Barnes, L. et al. (Ed.) Pathology and ge- netics. Head and neck tumours. World HealthOrganization Classification of Tumours. Lyon:IARCPress, 2008. p. 244.

Anonsen C, Dobie RA, Hoekema D, Huang T, Gown A. Carcinosarcoma of the floor of mouth. J Otolaryngol 1984;14: 215-20.

Takata T, Nikai H, Ogawa I, Ijuhin N. Ultrastruc- tural and immunohistochemical observations of a true malignant mixed tumor (carcinosarcoma) of the tongue. J Oral Pathol Med 1990;19:261-5.

Bleiweiss IJ, Huvos AG, Lara J, Strong EW. Car inosarcoma of the submandibular salivary gland: immunohistochemical findings. Can- cer 1992;69:2031-2035.

Carson HJ, Tojo DP, Chow JM, Hammadeh R, Raslan WF. Carcinosarcoma of salivary glands with unusual stromal components: report of two cases and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1995; 79:738-746.

Latkovich P, Johnson RL. Carcinosarcoma of the parotid gland: report of a case with cytohistolog- ic and immunohistological findings. Arch Pathol Lab Med 1998; 122:743-746.

Stuart-Harris R, Caldas C, Pinder SE, et al. Pro- liferation markers and survival in early breast cancer: a systematic review and meta-analysis of 85 studies in 32,825 patients. Breast. 2008;17:323-334.


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