Tehran University of Medical Sciences Journal of Craniomaxillofacial Research 2345-5489 4 1 2017 05 16 324 327 EN Faezeh Atri Department of Dental Prosthesis Technology, Dentistry Faculty, Tehran University of Medical Sciences, Tehran, Iran. Simindokht Zarati Department of Prosthodontics, Dentistry Faculty, Tehran University of Medical Sciences, Tehran, Iran. 2017 05 16 2017 05 16 This report describes the case of a 25-year-old female patient who initially was undergone of canine distalization and orthodontic space opening for replacement of congenitally missing lateral incisors. Then she received dental implants each side and after the healing period, cement retained prostheses was fabricated and delivered. Despite the fact that all the factors seemed fine, the right lateral implant failed after four months of cementation. Dental implant failure, especially in prosthetic phase, is a challenging issue in prosthodontics and it is important to find out the etiologies and associated factors. This case report discusses the probable reasons of early loading failure of cement retained implant restoration. Key words: Implant failure; lateral incisors missing; orthodontic space opening; osseointegration. https://jcr.tums.ac.ir/index.php/jcr/article/view/148 https://jcr.tums.ac.ir/index.php/jcr/article/download/148/168