Tehran University of Medical Sciences Journal of Craniomaxillofacial Research 2345-5489 4 3 2017 10 08 401 405 EN Moeen Hosseini Shirazi Department of Oral and Maxillofacial Prosthodontics, School of Dentistry, Tehran University of Medical Science, Tehran, Iran. Jamal Saker Department of Oral and Maxillofacial Prosthodontics, School of Dentistry, Tehran University of Medical Science, Tehran, Iran. Simindokht Zarrati Department of Oral and Maxillofacial Prosthodontics, School of Dentistry, Tehran University of Medical Science, Tehran, Iran. 2017 10 07 2017 10 07 Nasal cavity malignancies tend to make local aggressive growth. There are two possibilities for rehabilitation after a total rhinectomy: Operative reconstruction or a nasal prosthesis. Since the introduction of microvascular free flaps, most facial defects are now rehabilitated surgically and there are many available surgical options, however, for large deficiencies, regional as well as local flaps are definitely not cosmetically ideal. Moreover, patients requiring extensive midfacial prosthetic reconstruction will invariably have had previous radiotherapy, making placement and retention of implants more problematic and liable to fail. In this situation prosthetic rehabilitation can be an attractive alternative to the surgical reconstruction of the nose. This clinical report explains a step by step facial and intraoral prosthetic rehabilitation of a patient with total rhinectomy and partial maxillectomy with magnet-retained oral-nasal combination prosthesis. Keywords: Rhinectomy, Prosthetic Rehabilitation, Maxillectomy. https://jcr.tums.ac.ir/index.php/jcr/article/view/173 https://jcr.tums.ac.ir/index.php/jcr/article/download/173/190