Tehran University of Medical Sciences Journal of Craniomaxillofacial Research 2345-5489 5 1 2018 04 22 35 42 EN Shamsolmoulouk Najafi Department of Oral Medicine, International School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran. Department of Oral Medicine, Dental Research Center, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran. AND Department of Oral Medicine, Dental Research Center, International Campus of Tehran University of Medical Sciences, School of Dentistry, Tehran, Iran. AND Department of Oral Medicine, Tehran University of Medical Sciences, School of Dentistry, Tehran, Iran. Soheila Manifar Department of Oral Medicine, Emam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. Abbas Tafakhori Department of Neurology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. Sudabe Heydari Student of Dentistry, International Campus of Tehran University of Medical Sciences, School of Dentistry, Tehran, Iran. Mina Khayamzadeh Department of Oral Medicine, International Campus of Tehran University of Medical Sciences, School of Dentistry, Tehran, Iran. Mohammad Javad Kharazi Fard Department of Epidemiology and Biostatistics, Tehran University of Medical Sciences, Tehran, Iran. 2018 04 21 Introduction: Epilepsy is one of the most common chronic neurologic diseases. It has a great influence on quality of life, as it engages 1-3% of a society. Normally, 10% of the people of the society have experienced seizure once or several times during their lives. Regardingalldentistry aspects, they receive insufficient treatments, which might be due to the medical and economic status of them. Oral health is of paramount importance. Objective: This research aims at examining oral health status of the patients with epilepsy, comparing them with the non-patient ones from systemic point of view, and evaluating periodontal treatment needs. Materials and Methods: Sixty patients were randomly includedin this cross-sectional study. They were divided into 2 subgroups of partial and general (based on frequencies of seizures, type of seizure, and mental status). Sixty systemically non-patient people who referred to the Imam Khomeini Hospital for blood donation were randomly included in the study as the control group. They were medical and epilepsy history. Oral examinations were carried out. The Simplified Oral Hygiene Index (OHI-S), decay-missing-filled tooth (DMF-T), normal teeth abrasion rate (Abrasion Index), Prosthetic Index; periodontal treatment needs (CPITN) and Muhleman index were evaluated and a statistical comparison was made between the patient group and the control group and between the epilepsy subgroups. Results: OHI-S index, DMF-T index, Muhlemman index and Prosthetic index of the patient group was considerably higher than the one of the control group. About CPITN index, In mandible, the patient group has a significant difference with the control group, except in the area of the second left molar. Conclusion: Several factors contributed to worsening oral health status in the patient group as compared with the control group. For example, the effect of seizure itself, negative attitudes of dentists, and social and economic conditions. We propose to start oral treatments concurrent with the  treatments concerning epilepsy. Some special dental interventions were proposed for each subgroup. Keywords: Epilepsy, Oral healt, Periodontal. https://jcr.tums.ac.ir/index.php/jcr/article/view/210 https://jcr.tums.ac.ir/index.php/jcr/article/download/210/220