Tehran University of Medical Sciences Journal of Craniomaxillofacial Research 2345-5489 5 3 2018 09 15 131 135 Hasan Mirmohamad Sadeghi Department of Oral and Maxillofacial Surgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Masoume Fayazi Boroujeni Department of Oral and Maxillofacial Pathology, Shahrekord University of Medical Sciences, Shahrekord, Iran. Behnaz Poorian Department of Oral and Maxillofacial Pathology, lorestan University of Medical Sciences, Lorestan, Iran. 2019 01 06 Ameloblastic fibro-odontoma (AFO) is an uncommon benign mixed odontogenic tumor. AFO presents as a painless swelling in the posterior of mandible or maxilla that radiographically shows a well-defined radiolucent area containing various amounts of radiopaque deposits. Most cases occur before 20 years of age, with the average age of diagnoses being 9 years. This case report describes AFO affecting anterior mandible in the 29 month old girl. The lesion was surgically excised, and no recurrence was observed on 2 month follow-up. https://jcr.tums.ac.ir/index.php/jcr/article/view/270 https://jcr.tums.ac.ir/index.php/jcr/article/download/270/245