Tehran University of Medical Sciences Journal of Craniomaxillofacial Research 2345-5489 6 1 2019 08 24 51 54 Farnoosh Razmara Department of Oral and Maxillofacial Surgery, Tehran University of Medical Sciences, Tehran, Iran. Farzane Mosavat Department of Oral and Maxillofacial Radiology, Tehran University of Medical Sciences, Tehran, Iran. Forooz Keshani Dental Research Center, Department of Oral and Maxillofacial Pathology, Isfahan University of Medical Sciences, Isfahan, Iran. 2019 07 23 2019 07 26 The lipoma is 5% of benign tumors and 25 to 50% of soft tissue tumors. It most occurs in the upper trunk area, neck and the extremities. But it is rare in the oral and maxillofacial area. It is a benign lesion composed of fat mature adipose tissue that Separated with fibrous septa and surrounded with a thin fibrous capsule. Jaw Intraosseous lipoma is very rare, and its prevalence has been mentioned in articles 1.0%. The case of this manuscript was a 33-year-old woman who referred to an orthodontic specialist with a complaint about the tooth crowding and requesting orthodontic treatment. Based on clinical, radiography and histopathology finding, a diagnosis of intraosseous lipoma of the mandible was made. https://jcr.tums.ac.ir/index.php/jcr/article/view/291 https://jcr.tums.ac.ir/index.php/jcr/article/download/291/262