Tehran University of Medical Sciences Journal of Craniomaxillofacial Research 2345-5489 6 2 2019 10 13 66 72 Zahra Ghoncheh Department of Oral and Maxillofacial Radiology, School of Dentistry, International Campus Tehran University of Medical Sciences, Tehran, Iran. Behrang Moghaddamzadeh Department of Oral and Maxillofacial Radiology, School of Dentistry, International Campus Tehran University of Medical Sciences, Tehran, Iran. Hanieh Kaviani Department of Oral and Maxillofacial Radiology, Dental School, Tehran University of Medical Sciences International Campus, Tehran, Iran. Golshan Jamali Department of Oral and Maxillofacial Radiology, Dental School, Tehran University of Medical Sciences International Campus, Tehran, Iran. Maral Feizi Private Practice, Tehran, Iran. 2019 08 07 2019 09 27 Objectives: This study aimed to measure the buccal cortical plate thickness in the mandible of dentate adults in an Iranian population using cone-beam computed tomography (CBCT). Materials and Methods: Eighty CBCT images were evaluated in this study using NNT Viewer 6.0 software. Images had high-resolution and had been taken by NewTom CBCT scanner with 11 x 8cm field of view. Measurements were made using the digital ruler of the software with 0.1mm accuracy. All analyses were performed by two observers: an oral and maxillofacial radiologist and a general dentist. In case of disagreement between the observers, measurements were repeated and the mean value was used for analysis. Data were analyzed by using linear regression. Results: The results showed that the thickness of buccal cortical plate increased from the canine towards the second molar site. The second molar site had the greatest density and thickness. Gender had a significant effect on the thickness of buccal cortical plate (P<0.05) but the effect of right/ left quadrant was not significant (P>0.05). The effect of age on this thickness was insignificant in some (P>0.05) and significant (P<0.05) in some other areas such that by an increase in age of patients, this thickness decreased (i.e. at the apex of canine, second premolar and second molar teeth). Conclusion: The buccal cortical plate thickness of the mandible increases from the anterior towards the posterior region, and the second molar area has the greatest thickness and density suitable for placement of orthodontic mini-implants or harvesting autogenous grafts. Keywords: Buccal cortical plate; Mandible; Cone-beam computed tomography; Mini-implant. https://jcr.tums.ac.ir/index.php/jcr/article/view/296 https://jcr.tums.ac.ir/index.php/jcr/article/download/296/265