Tehran University of Medical Sciences Journal of Craniomaxillofacial Research 2345-5489 7 2 2020 10 03 91 97 Chitamani Sobhan Nyer Firdoose Department of Oral & Maxillofacial Surgery, Riyadh Specialized Dental Center, Ishbiliyah, Riyadh, Saudi Arabia. Mohamed Alsaleh Department of Implantology, Riyadh Specialized Dental Center, Ishbiliyah, Riyadh, Saudi Arabia. 2020 07 08 2020 08 21 The mandibular canal and the mental foramina are constant structures that remain largely bilaterally symmetrical except for variations in shape and size within certain limits. Structural alterations such as enlargement of mental foramen and the mandibular canal are rare and usually recorded as incidental finding on plain radiographs. This enlargement may be associated with multiple factors. We present a unique case of bilateral wide mental foramina with enlarged mandibular canal in a 56-year-old asymptomatic male. Keywords: Mental foramen; Anatomical variation; Mandibular canal; Cone beam computed tomography (CBCT); Nerve enlargement. https://jcr.tums.ac.ir/index.php/jcr/article/view/333 https://jcr.tums.ac.ir/index.php/jcr/article/download/333/295