Tehran University of Medical Sciences Journal of Craniomaxillofacial Research 2345-5489 2 3-4 2016 02 17 112 115 EN Foad Akhoondinasaba Department of Prosthodontics, School of Dental, Tehran University of Medical Sciences, Tehran, Iran. Mehran Bahrami Department of Prosthodontics AND Dental Research Center, School of Dental, Tehran University of Medical Science, Tehran, Iran. Azra Mohiti Department of Oral Disease, School of Dentistry, Shahid Sadoughi University of Medical Science, Yazd, Iran. Maryam Vahdat Student, School of Dentistry, Shahid Sadughi University of Medical Sciences, Yazd, iran. 2016 02 17 2016 02 17 Introduction: Saliva as a simple non-invasive method of gaining body fluids has been used to detect the thyroid hormones. A single method for determining these hormones has not been clearly stated in the literature. Furthermore, thyroid diseases would affect the salivary glands and may compromise salivary flow. Materials and Methods: A comprehensive search was conducted using PubMed and Medline. Conclusion: Saliva can successfully be used as a non-invasive method for determining thyroid hormones and for detecting and monitoring thyroid dysfunctions. Thyroid dysfunctions also have a great impact on salivary gland functions and saliva. https://jcr.tums.ac.ir/index.php/jcr/article/view/39 https://jcr.tums.ac.ir/index.php/jcr/article/download/39/73