Tehran University of Medical Sciences Journal of Craniomaxillofacial Research 2345-5489 12 1 2025 08 25 61 64 Javad Sarabadani Department of Oral Medicine, Faculty of Dentistry and Dental Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. Armaghan Salehi Student Research Committee, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran. Ali Labafchi Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Kerman University of Medical Sciences, Kerman, Iran. 2025 03 14 2025 07 11 Blood vessel defects or endothelial proliferation can cause vascular lesions. Capillary hemangiomas are produced in a connective tissue stroma by small capillaries surrounded by a layer of endothelial cells. Numerous procedures, including excisional surgery, sclerotherapy, and laser irradiation, are used to treat these conditions. This study presents a clinical case of surgical removal of a hemangioma in the buccal mucous membrane using a defocused irradiation mode of a diode laser. A 47-year-old woman with a purple lesion in the mucous membrane of the right cheek was referred to Jihad Dental Clinic. The Diode laser, with a wavelength of 980nm, was selected for treating the lesion in defocused mode at an output power of 2.5 W in continuous mode. In surgery, no bleeding was observed, which provided the surgeon with better vision and resulted in a minimally invasive procedure. Due to fewer postoperative complications, using laser diodes in the treatment of oral hemangioma as a conservative approach, and providing simple surgical procedures with minimal side effects, may be beneficial to both patients and doctors.  Keywords: Hemangioma; Lasers; Semiconductor; Vascular malformation. https://jcr.tums.ac.ir/index.php/jcr/article/view/531 https://jcr.tums.ac.ir/index.php/jcr/article/download/531/442