Tehran University of Medical Sciences Journal of Craniomaxillofacial Research 2345-5489 2026 2 2026 08 25 246 250 Rezhat Abbas Department of Oral Pathology, Maulana Azad Institute of Dental Sciences, New Delhi, India. Suheel Hamid Latoo Department of Oral Pathology, Government Dental College & Hospital, Srinagar, Jammu & Kashmir, India. 2025 12 14 2026 07 12 Polymorphous adenocarcinoma is an uncommon neoplasm of the salivary glands, exhibiting a strong predilection for the minor salivary glands. It is distinguished by its characteristic polymorphous histologic appearance, infiltrative growth pattern, and relatively low potential for metastasis. A 45-year-old male presented with pain and swelling in the posterior palate persisting for two months, accompanied by difficulty in mastication and swallowing. Intraoral examination revealed a well-defined, ovoid swelling on the right side of the palate, displaying a nodular surface and erythematous margins. An excisional biopsy was performed, and histopathological evaluation confirmed the diagnosis of polymorphous adenocarcinoma.  Keywords: Polymorphous adenocarcinoma; Polymorphous low-grade adenocarcinoma; Salivary gland neoplasm. https://jcr.tums.ac.ir/index.php/jcr/article/view/602 https://jcr.tums.ac.ir/index.php/jcr/article/download/602/504