Tehran University of Medical Sciences Journal of Craniomaxillofacial Research 2345-5489 13 3 2026 10 24 365 370 Mahdi Zahedi Department of Prosthodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran. Azam Sadat Mostafavi Department of Prosthodontics, Dental Research Center, Dentistry Research Institute, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran. 2026 05 20 2026 10 02 This clinical report describes the prosthetic rehabilitation of a patient following a maxillary resection performed to treat Mucoepidermoid Carcinoma. Following hemi maxillectomy and total resolution of the tumor, implant placement was digitally planned to use the dual-scan technique, and implants were surgically inserted with the aid of a printed acrylic surgical guide. After successful osseointegration, a removable implant-supported overdenture retained by stud attachments was fabricated to improve prosthetic stability and minimize rotational and translational displacement under functional loading.  Keywords: Maxillary defect; Implant-supported overdenture; Prosthetically driven implant insertion; Maxillofacial prosthesis. https://jcr.tums.ac.ir/index.php/jcr/article/view/662 https://jcr.tums.ac.ir/index.php/jcr/article/download/662/518