Tehran University of Medical Sciences Journal of Craniomaxillofacial Research 2345-5489 3 3 2016 08 15 230 234 EN Shiva Shirazian Oral medicine Department, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran Naghmeh Bahrami Craniomaxillofacial Research center, Tehran University of Medical Sciences, Tehran, Iran. Oral and Maxillofacial Surgery Department, School of Dentistry,Tehran University of Medical Sciences, Tehran, Iran. Iranian Tissue Bank & Research Center, Tehran University of Medical Sciences, Tehran, Iran. 2016 09 28 2016 09 28 Metastatic lesions represent 1-8% of all malignant tumors of the mouth and jaws, which are regarded as rare sites of metastases from different primary tumors. Metastases in mouth soft tissue are also rare, and within these it is on the gums where they more frequently occur. Primary tumors which metastasize to the mouth are most commonly: lung, breast, and kidney. Clear cell carcinoma is the most frequent cancer of the kidney (60-80% of cases). This tumor has a great propensity to metastasis. We report a case of a 45-year-old man with renal cell carcinoma in which the gingival symptoms (metastatic tumor) preceded the discovery of the primary lesions. https://jcr.tums.ac.ir/index.php/jcr/article/view/92 https://jcr.tums.ac.ir/index.php/jcr/article/download/92/132