Original Article

A comparison of tissue conditioner alone versus tissue conditioner with chx for treatment of the denture stomatitis in older adults

Abstract

Objectives: Denture stomatitis (DS) is a multifactorial common disorder of removable denture wearers. Incorporation of antimicrobial agents in the lining materials may be an effective treatment for this condition. The purpose of this study is to compare of tissue conditioner alone versus tissueconditioner with CHX for treatment of the DS.Materials and Methods: Thirty six denture-wearing patients suffering from different stages of DS were investigated this clinical trial. Patients were assessed clinically and then randomlydivided to two groups: test (TC containing CHX) and control (same TC without CHX) Clinical effectiveness of each treatment was measured using clinical indexes consist of lesion size, color of lesion and sore mouth on day0, day 1, day 3 and day 7.Results: Findings showed that both treatments resulted in decreasing the lesion size with statistically significant differences between control and test groups. The percentage of the patientwith pink lesions increased and the number of patients with ruby and red lesion decreased over treatment period with statistically significant differences between groups. Both treatments led todecrease of the pain without any statistically significant difference between groups.Conclusions: It was concluded that of TC alone and TC with CHX are an treatment for DS. It seems that adding CHX to T.C has a statistically significant positive effect on lesion size and colorcompared to T.C alone.Keywords: CHX, Denture stomatitis, Tissue conditioner.

Ruby J, Barbeau J. The buccale puzzle: The symbi- otic nature of endogenous infections of the oral cavity. Can J Infect Dis. 2002; 13(1):34-41.

Coco B, Bagg J, Cross L, Jose A, Cross J, Ramage G. Mixed Candida albicans and Candida glabrata populations associated with the pathogenesis of denture stomatitis. Oral microbiology and immu- nology. 2008; 23(5):377-83.[3] Altarawneh S, Bencharit S, Mendoza L, Curran A, Barrow D, Barros S, et al. Clinical and histologi- cal findings of denture stomatitis as related to in- traoral colonization patterns of Candida albicans, salivary flow, and dry mouth. J Prosthodont. 2013;22(1):13-22.

Shulman J, Rivera‐Hidalgo F, Beach M. Risk factors associated with denture stomatitis in the United States. J Oral Pathol Med. 2005; 34(6):340-6.

Martori López E, Ayuso Montero R, Martínez Gomis J, Viñas M, Peraire Ardèvol M. Risk factors for denturerelated oral mucosal lesions in a geri- atric population. J Prosthet Dent, 2014, vol 111, num 4, p 273-279. 2014.

Gendreau L, Loewy ZG. Epidemiology and etiol- ogy of denture stomatitis. J Prosthodont. 2011;20(4):251-60.

Salerno C, Pascale M, Contaldo M, Esposito V, Busciolano M, Milillo L, et al. Candida-associated denture stomatitis. Med Oral Patol Oral Cir Bucal.2011; 16(2):e139-43.

Ercalik‐Yalcinkaya S, Özcan M. Association be- tween oral mucosal lesions and hygiene habits in a population of removable prosthesis wearers. J Prosthodont. 2015; 24(4):271-8.

Lynge Pedersen A, Nauntofte B, Smidt D, Torpet LA. Oral mucosal lesions in older people: relation to salivary secretion, systemic diseases and medi- cations. Oral Dis. 2015; 21(6):721-9.

Amin WM, Al-Ali MH, Salim NA, Al-Tarawneh SK. A new form of intraoral delivery of antifungal drugs for the treatment of denture-induced oral candidosis. Eur J Dent. 2009; 3(4):257-66.

Ryalat S, Darwish R, Amin W. New form of ad- ministering chlorhexidine for treatment of den- ture-induced stomatitis. Therapeutics and clinical risk management. 2011;7:219.

Arendorf T, Walker D. Denture stomatitis: a re- view. J Oral Rehabil. 1987;14(3):217-27.

Jeganathan S, Lin CC. Denture stomatitis—a re- view of the aetiology, diagnosis and management. Aust Dent J. 1992; 37(2):107-14.

DePaola LG, Minah GF, Elias SA, Eastwood GW, Walters RA. Clinical and microbial evaluation of treatment regimens to reduce denture stomatitis. Int J Prosthodont. 1990; 3(4).

Chase WW. Tissue conditioning utilizing dynamic adaptive stress. J Prosthet Dent. 1961; 11(5):804-15.

Bamigboye S, Dosumu O, Ajayi D. Microwave disinfection of maxillary and mandibular denture bases contaminated with Candida Albican. Afr J Med Med Sci. 2015; 44(3):221-8.

Orsi IA, Andrade VG, Bonato PS, Raimundo LB, Herzog DS, Borie E. Glutaraldehyde release from heat-polymerized acrylic resins after disinfection and chemical and mechanical polishing. Braz Dent J. 2011; 22(6):490-6.

Orsi IA, Junior AG, Villabona CA, Fernandes FHCN, Ito IY. Evaluation of the efficacy of chemi- cal disinfectants for disinfection of heat‐polymer- ised acrylic resin. Gerodontology. 2011; 28(4):253-7.

Vasconcelos LR, Consani RLX, Mesquita MF, Sinhoreti MAC. Effect of chemical and micro- wave disinfection on the surface microhardness of acrylic resin denture teeth. J Prosthodont. 2013;22(4):298-303.

Salim N, Moore C, Silikas N, Satterthwaite J, Ra- utemaa R. Chlorhexidine is a highly effective topi- cal broad-spectrum agent against Candida spp. Int J Antimicrob Agents. 2013; 41(1):65-9.

Bertolini MM, Portela MB, Curvelo JAR, Soares RM, Lourenço EJ, Telles DM. Resins-based den- ture soft lining materials modified by chlorhex- idine salt incorporation: an in vitro analysis of antifungal activity, drug release and hardness. Dental Materials. 2014; 30(8):793-8.

Mylona Z, Gogos C, Economides N. Influence of Irrigation with NaOCl and chlorhexidine on mi- croleakage. Balk J Dent Med. 2015; 19(1):38-42.

Patel M, Cruchley A, Coleman D, Swai H, Bra- den M, Williams D. A polymeric system for the intra-oral delivery of an anti-fungal agent. Bioma- terials. 2001; 22(17):2319-24.

Salim N, Moore C, Silikas N, Satterthwaite JD, Ra- utemaa R. Fungicidal amounts of antifungals are released from impregnated denture lining mate- rial for up to 28 days. J Dent. 2012; 40(6):506-12.

Hiraishi N, Yiu C, King N, Tay F, Pashley DH.Chlorhexidine release and water sorption char acteristics of chlorhexidine-incorporated hydrophobic/hydrophilic resins. Dental materials. 2008;24(10):1391-9.

Pina Gd, Lia EN, Berretta AA, Nascimento AP, Torres EC, Buszinski AF, et al. Efficacy of Prop- olis on the Denture Stomatitis Treatment in Old- er Adults: A Multicentric Randomized Trial. Ev- idence-Based Complementary and Alternative Medicine. 2017; 2017.

Marín Zuluaga DJ, Gómez Velandia OC, Claui- jo R, Diana M. Denture‐related stomatitis man- aged with tissue conditioner and hard autopoly- merising reline material. Gerodontology. 2011;28(4):258-63.

Sanita PV, Machado AL, Pavarina AC, Massuca- to EMS, Colombo AL, Vergani CE. Microwave denture disinfection versus nystatin in treating patients with well-controlled type 2 diabetes and denture stomatitis: a randomized clinical trial.2014

Neppelenbroek K, Pavarina AC, Palomari Spo- lidorio D, Sgavioli Massucato E, Spolidório LC, Vergani CE. Effectiveness of microwave disin- fection of complete dentures on the treatment of Candida‐related denture stomatitis. J Oral Reha- bil. 2008; 35(11):836-46.

Uludamar A, Gökhan Özye şil A, Ozkan YK. Clinical and microbiological efficacy of three different treatment methods in the management of denture stomatitis. Gerodontology. 2011; 28(2):104-10.

Lamey P, Lewis M, MacDonald D. Treatment of candidal leukoplakia with fluconazole. Br Dent J..1989; 166(8):296-8.

Wright P, Clark P, Hardie J. Clinical Science The Prevalence and Significance of Yeasts in Persons Wearing Complete Dentures with Soft-lining Ma- terials. J Dent Res. 1985; 64(2):122-5.

Files
IssueVol 4, No 3 (Summer 2017) QRcode
SectionOriginal Article(s)
Keywords
CHX Denture stomatitis Tissue conditioner

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
1.
Kadkhoda Z, Pirmoradian Najafabadi M, Chokami Rafiei S, Abolhasani A, Fayazi F. A comparison of tissue conditioner alone versus tissue conditioner with chx for treatment of the denture stomatitis in older adults. J Craniomaxillofac Res. 2017;4(3):395-400.