Original Article

The effect of the submucosal injection of dexamethasone on postoperative discomfort after impacted mandibular third molar surgery

Abstract

Introduction: Our study was designed to assess the effect of the submucosal injection of dexamethasone on postoperative discomfort after surgical removal of impacted mandibular third molars.Materials and methods: Twenty six patients with bilaterally bony impacted mandibular third molars were recruited to this split mouth study. On the study side, prior to surgery, 8 mg of dexamethasone was injected in buccal vestibule submucosally, while the control side received no steroid. Complications such as swelling, trismus and infection were evaluated postoperatively.Results: The results showed that the patients experienced significantly less swelling  (p=  0.001)  on  study  side  on  the  3rd   and  7th   postoperative  days compared to the control side. The amount of trismus was significantly less (p=0.001) after submucosal injection of dexamethasone on both time intervals.Conclusion: Perioperative submucosal injection of dexamethasone can significantly reduce postoperative swelling and trismus after surgical removal of the impacted teeth.

Thomas D, Walker R, Smith A, Shepherd J. The provision of oral surgery services in England and Wales 1984-1991. British Dental Journal 1994;176: 215 – 219.

Blondeau, F. and Daniel NG. Extraction of impacted mandibular third molars: postoperative complications and their risk factors. J Can Dent Assoc, 2007. 73(4): p. 325.

Kim K, Brar P, akubowski J, Kaltman S, Lopez E.The use of corticosteroids and nonsteroidal anti-inflammatory medication for the management of pain and inflammation after third molar surgery: a review of the literature. Oral Surg Oral Med Oral Pathol Oral RadiolEndod.2009 ;107:630-40.

Lara-de la Fuente R. Steroid infiltrations inorthopedics.ActaOrtop Mex. 2011;25:12-6.

Graziani F, D'Aiuto F, Arduino PG, Tonelli M, Gabriele M. Perioperative dexamethasone reduces post-surgical sequelae of wisdom tooth removal. A split-mouth randomized double- masked clinical trial. Int J Oral Maxillofac Surg.2006;35:241-6.

Neff SP, Stapelberg F, Warmington A.Excruciating perineal pain after intravenous dexamethasone. Anaesth Intensive Care. 2002;30:370-1.

Gunal I, Karatosun V. Avascular necrosis of the femoral heads after single corticosteroid injection. CMAJ 2006;175:31.

Holland CS. The influence of methylprednisolone on post-operative swelling following oral surgery. Brit J Oral and Maxillofac Surg 1987;25: 293-299.

Tiigimae-Saar J, Leibur E, Tamme T. The effect of prednisolone on reduction of complaints after impacted third molar removal Stomatologia.2010;12:17-22.

Markiewicz MR, Brady MF, Ding EL, Dodson TB. Corticosteroids reduce postoperative morbidity after third molar surgery: a systematic review and meta-analysis. J Oral Maxillofac Surg. 2008;66:1881-94.

Dodson TB. Corticosteroid administration in oral and orthognathic surgery. Evid Based Dent.2011; 12:49-50.

Grossi GB, Maiorana C, Garramone RA, Borgonovo A, Beretta M, Farronato D, Santoro F. Effect of submucosal injection of dexamethasone on postoperative discomfort after third molar surgery: a prospective study. J Oral Maxillofac Surg. 2007 Nov; 65(11):2218-26.

Majid OW, Mahmood WK.. Effect of submucosal and intramuscular dexamethasone on postoperative sequelae after third molar surgery: comparative study. Br J Oral Maxillofac Surg,2011. 49(8): p. 647-52.

Files
IssueVol 2, No 1-2 (Winter/Spring 2015) QRcode
SectionOriginal Article(s)
Keywords
Third molar Swelling Trismus Dexamethasone

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
1.
Mohammadi F, Hasheminasab M, Asgarian A, Zahedanaraki A. The effect of the submucosal injection of dexamethasone on postoperative discomfort after impacted mandibular third molar surgery. J Craniomaxillofac Res. 2015;2(1-2):91-94.