Epidemiological features of oral squamous cell carcinoma
,
Abstract
Background: Squamous cell carcinoma (SCC) is the most common head and neck cancer. According to the role of epidemiological data in planning and effective interventions, the aim for the current study was a five-year review of oral squamous cell carcinoma. Materials and Methods: In this cross-sectional study, the data was derived from 76 recorded files of patients with oral SCC (OSCC) in Shariati hospital at the Tehran University of Medical Sciences from 2010 to 2015. The data included demographic variables, risk factors and lesion characteristics. The collected data has been analyzed by SPSS software and descriptive analysis was presented. Results: In this study 52 patients were male (68.4%) and 24 patients were female (31.6%). The mean age of patients was 60.5 ± 12.80 years. The prevalence of OSCC among men was 2.2 times more than women. The most common sites of tumor were buccal mucosa (36.8%) and then mandibular ridge (34.2%) and the most common clinical symptoms of tumor were painful tooth/teeth which are not mobile (69.7%) and ulcer (64.5%). Based on histological grading, 64.5% of patients had well-differentiated lesions. Conclusion: The results of this study indicate that OSCC was more common in men and seniors. It also has involved buccal mucosa and mandibular ridge. The majorities of OSCC lesions were well-differentiated in the oral cavity, and were in stages two and three in TNM system.
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[2] Fritz A, Percy C, Jack A, Shanmugaratnam K,Sobin L, Parkin DM, et al. International classification of diseases for oncology. 3rd ed. Geneva,Switzerland: World Health Organization; 2000.
[3] Andisheh-Tadbir A, Mehrabani D, Heydari ST(2008) Epidemiology of squamous cell carcinoma of the oral cavity in Iran. J Craniofac Surg 19(6),1699-1702.
[4] Anneroth G, Batsakis J, Luna M (1987) Review ofthe literature and a recommended system of malignancygrading in oral squamous cell carcinomas.Scand J Dent Res 95(3), 229-249.
[5] Ariyawardana A, Vithanaarachchi N (2005) Awarenessof oral cancer and precancer among patients attending a hospital in Sri Lanka. Asian Pac J CancerPrev 6(1), 58-61.
[6] Arotiba GT, Ladeinde AL, Oyeneyin JO, NwawoloC, Banjo AA, Ajayi OF (2006) Malignant orofacial neoplasms in Lagos, Nigeria. East Afr Med J 83(3), 62-68.
[7] Bhurgri Y (2005) Cancer of the oral cavity trends in Karachi South (1995-2002). Asian Pac J Cancer Prev 6(1), 22-26.
[8] Brandizzi D, Chuchurru JA, Lanfranchi HE, Cabrini RL (2005) Analysis of the epidemiological features of oral cancer in the city of Buenos Aires.Acta Odontol Latinoam 18(1), 31-35.
[9] Chamani G, Zarei MR, Rad M, Hashemipoor M, Haghdoost AA (2009) Epidemiological Aspects of Oral and Pharyngeal Cancer in Kerman Province, South Eastern Iran Iranian J Publ Health 38(2),90-97.
[10] Chidzonga MM, Mahomva L (2006) Squamous cell carcinoma of the oral cavity, maxillary antrum and lip in a Zimbabwean population: a descriptive epidemiological study. Oral Oncol 42(2), 184-189.
[11]Chitapanarux I, Lorvidhaya V, Sittitrai P et al.(2006) Oral cavity cancers at a young age: analysis of patient, tumor and treatment characteristicsin Chiang Mai University Hospital. Oral Oncol 42(1), 83-88.
[12] Eshghyar NO, Motahari P, Khorshidian A (2005) Evaluation of clinical and histological parameters in patients with oral squamous cell carcinomareferred to Tehran Faculty of Dentistry (1966 –2002). J Islamic Dent Assoc Iran 17(2), 62-67.
[13]Huang CH, Chu ST, Ger LP, Hou YY, Sun CP (2007) Clinicopathologic evaluation of prognostic factors for squamous cell carcinoma of the buccal mucosa. J Chin Med Assoc 70(4), 164-170.
[14] Iamaroon A, Pattanaporn K, Pongsiriwet S et al.(2004) Analysis of 587 cases of oral squamous cell carcinoma in northern Thailand with a focus on young people. Int J Oral Maxillofac Surg 33(1),84-88.
[15] Ma X, Yu H (2006) Global burden of cancer. Yale J Biol Med 79(3-4), 85-94.
[16] Maleki D, Ghojazadeh M, Mahmoudi SS et al. (2015) Epidemiology of Oral Cancer in Iran: a Systematic Review. Asian Pac J Cancer Prev16(13), 5427-5432.
[17] Mousavi SM, Gouya MM, Ramazani R, Davanlou M, Hajsadeghi N, Seddighi Z (2009) Cancer incidenceand mortality in Iran. Ann Oncol 20(3),556-563.
[18] Murugan AK, Hong NT, Cuc TT et al. (2009) Detectionof two novel mutations and relatively high incidence of H-RAS mutations in Vietnamese oralcancer. Oral Oncol 45(10), e161-166.
[19] Neville B, Damm D, Allen C, Bouguot JE (2009)Oral and maxillofacial pathology 2nd ed. 2009; chap 10: . 2 nd edn; Philadelphia: W.B saunders[20]Nutter FW (1999) Understanding the nterrelationships Between Botanical, Human, and Veterinary Epidemiology: The Ys and Rs of It All. Ecosystem Health 5(3), 131-140.
[21]Pakfetrat A, Falaki F, Esmaily HO, Shabestari S (2010) Oral cancer knowledge among patients referred to Mashhad Dental School, Iran. Arch IranMed 13(6), 543-548.
[22] Perez RS, De Freitas SM, Dediritis RA, Rapopart A, Denardin OVP, Sobrinho JOA (2007) Epidemiologic study of squamous cell carcinoma of the mouth and pharynx. Int Arch otorhinolaryngol
11(3), 271-277.
[23] Regezi JA, Sciubba JJ, Jordan RCK (2009) Oral pathology: clinical pathologic correlations, 5 th edn; Philadelphia: W.B saunders. [24]Sankaranarayanan R, Ramadas K, Amarasinghe H, Subramanian S, Johnson N (2015) Oral Cancer: Prevention, Early Detection, and Treatment. In:Gelband H, Jha P, Sankaranarayanan R, Horton S, eds. Cancer: Disease Control Priorities, Third Edition (Volume 3). Washington DC: 2015 International Bank for Reconstruction and Development /The World Bank.
[25] Sargeran K, Murtoma H, Safavi SM, Vehkalahti M, Teronen O (2006) Malignant oral tumors in Iran: Ten-year analysis on patient and tumor characteristics of 1042 patients in Tehran. J Craniofac Surg 17(6), 1230-1233.
[26] Sargeran K, Murtomaa H, Safavi SM, Teronen O (2009) Delayed diagnosis of oral cancer in Iran: challenge for prevention. Oral Health Prev Dent 7(1), 69-76.
[27] Warnakulasuriya S (2010) Living with oral cancer: epidemiology with particular reference to prevalence and life-style changes that influence survival. Oral Oncol 46(6), 407-410.
[28] Yahalom R, Dobriyan A, Vered M, Talmi YP, Teicher S, Bedrin L (2008) A prospective study of surgical margin status in oral squamous cell carcinoma: a preliminary report. J Surg Oncol 98(8),572-578.
[29] Zaidi M, Mallick A (2014) A study on assessment of mast cells in oral squamous cell carcinoma. Ann Med Health Sci Res 4(3), 457-460.
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| Issue | Vol 5, No 3 (Summer 2018) | |
| Section | Original Article(s) | |
| Keywords | ||
| Oral cancer Squamous cell carcinoma Oral squamous cell carcinoma. | ||
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How to Cite
1.
Jafari A, Karimi A, Salamat M. Epidemiological features of oral squamous cell carcinoma. J Craniomaxillofac Res. 2018;5(3):119-124.
