Cold Ceramic in Endodontics Treatments: A Review
Abstract
Introduction: Cold Ceramic (CC) is designed to meet the ideal criteria for root filling materials, offering effective sealing, biocompatibility, non-toxicity, dimensional stability, insolubility in tissue fluids, radiopacity, and ease of handling. It sets in the presence of moisture, making it suitable for various endodontic applications such as root-end filling, root perforation repair, apical barriers in teeth with open apices, and pulp capping. This study aims to evaluate cold ceramic’s clinical outcomes and applications as presented in case reports. Materials and Methods: A comprehensive literature search was conducted to identify published case reports and case series on the clinical application of cold ceramics in endodontics from January 2000 to April 2024. Databases searched included PubMed, MEDLINE, Scopus, Web of Science, Cochrane Library and Google Scholar. The search terms used were “cold ceramic,” “bio ceramic,” “endodontics,” “case report,” “clinical outcomes,” and “dental materials”. Articles in English and Persian were included. Patient demographics, cold ceramic brand, clinical procedures, outcomes, follow-up periods, and any complications were extracted. Quality assessment of the included case reports was performed using the CARE guidelines.Results: After removing duplicates and screening titles and abstracts, 7 case reports and 2 case series met the inclusion criteria. The reviewed case reports included 16 patients (9 female and 7 male) with a mean age of 29.25±1.2. Clinical outcomes were generally favorable, with high success rates and minimal complications reported. Conclusion: All cases demonstrated radiographic and clinical healing and an absence of postoperative pain or infection during follow-up periods ranging from 3 months to 4 years. cold ceramics provide promising success rates and negligible complications in various clinical endodontic scenarios. Keywords: Apexification; Biocompatibility; Case report; Cold ceramic; Endodontics; Root canal; Root perforation; Sealing ability; Treatment.
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2. Torabinejad M, Watson TF, Pitt Ford TR. Sealing ability of a mineral trioxide aggregate when used as a root end filling material. J Endod. 1993;19(12):591-595.
3. Parirokh M, Torabinejad M. Mineral trioxide aggregate: a comprehensive literature review—Part I: chemical, physical, and antibacterial properties. J Endod. 2010;36(1):16-27.
4. Parirokh M, Torabinejad M. Mineral trioxide aggregate: a comprehensive literature review—Part II: leakage and biocompatibility investigations. J Endod. 2010;36(2):190-202.
5. Modaresi J, Parirokh M, Asgary S. Evaluation of the sealing ability of a new endodontic cement (Cold Ceramic) as root-end filling material. J Endod. 2005;31(2):102-105.
6. Asgary S, Eghbal MJ, Parirokh M, Ghoddusi J, Kheirieh S, Brink F. Comparison of mineral trioxide aggregate’s composition with Portland cements and a new endodontic cement. J Endod. 2009;35(2):243-250.
7. Asgary S, Eghbal MJ, Parirokh M, Ghoddusi J, Kheirieh S, Brink F. A comparative study of the effect of Cold Ceramic and MTA on the healing of furcation perforations in dogs. J Endod. 2008;34(8):923-927.
8. Modaresi J, Asgary S. Cold Ceramic: A new endodontic filling material. Iran Endod J. 2006;1(1):1-5.
9. Modaresi J, Khademi A, Hemati H, Mokhtari F. Histological evaluation of ProRoot mineral trioxide aggregate and Cold ceramic as root-end filling materials in animal models. Dent Res J (Isfahan). 2023;20:58.
10. Khedmat S, Sarraf P, Seyedjafari E, Sanaei-Rad P, Noori F. Comparative evaluation of the effect of cold ceramic and MTA-Angelus on cell viability, attachment and differentiation of dental pulp stem cells and periodontal ligament fibroblasts: an in vitro study. BMC Oral Health. 2021;21:628.
11. Mokhtari F, Modaresi J, Javadi G, Davoudi A, Badrian H. Comparing the Marginal Adaptation of Cold Ceramic and Mineral Trioxide Aggregate by Means of Scanning Electron Microscope: An In vitro Study. J Int Oral Health. 2015;7:7-10.
12. Modaresi J, Yavari SA, Dianat SO, Shahrabi S. A comparison of tissue reaction to MTA and an experimental root-end restorative material in rats. Aust Endod J. 2005;31:69-72.
13. Akhavan A, Parashos P, Razavi SM, Davoudi A, Shadmehr E. Hard tissue reaction to mineral trioxide aggregate and experimental root-end filling material in guinea pig mandibles. J Dent Sci. 2017;12:107-11.
14. Rasteh B, Basir L, Taravati S, Khataminia M. Evaluation and comparison of mineral trioxide aggregate and cold ceramic in primary tooth pulpotomy: Clinical and radiographic study. J Family Med Prim Care. 2023;12:3068-74.
15. Modaresi J, Nasr N. Nonsurgical Endodontic Management of Large Periapical Lesion with Cold Ceramic: A Literature Review and Case Series. Iran Endod J. 2023;18:113-21.
16. Modaresi J, Mirzaeeian A, Almodaresi Z, Mousavi R. Apexification of an Immature Tooth with Cold Ceramic: A Case Report. J Isfahan Dent Sch. 2020;16:345-51.
17. Marzoughi Shirin, Salari Moghaddam Reza, Faghihian Reyhaneh, MORADI SAMANEH, SOLTANI MEHDI. Apexification of an Immature Permanent First Molar Tooth with Cold Ceramic: A Case Report. JOURNAL OF ISFAHAN DENTAL SCHOOL[Internet]. 2022;17(4 ):467-473.
18. AYATOLLAHI FATEMEH, Zahedinejad Amirali, Bagheri Hariri Aida, MODARESI JALIL. A case report of successful apexification in mandibular second molar, using cold ceramics”,. JOURNAL OF RESEARCH IN DENTAL SCIENCES[Internet]. 2023;20(1 (75) ):70-75.
19. Ghabraei S, Bolhari B, Hashemi N, Gharehchahi H. Conservative management of an advanced external cervical resorption with internal approach using bio-ceramic materials: A case report. Clin Case Rep. 2024;12:e8378.
20. Modaresi J, Almodaresi z, Mousavi R, Mirzaeeian A. Successful Root Canal Treatment with Cold Ceramic: A Case Report. J Mashhad Dent Sch. 2021;45:309-13.
21. ModaresiJ,Yazdani RostamA,MahiniF,NasrN.ColdCeramicasaRootCanalFillingMaterial:ACaseSeries.JDentSch2024;42(1):49-55.
22. Modaresi J, Almodaresi Z, Mousavi R, Mirzaeeian A, Hosseini SAS. Successful management of a tooth with canal obstruction using "cold ceramic". Dent Res J (Isfahan). 2021;18:77.
23. Modaresi J, Parashos P, Mousavi R, Mirzaeeian A, Almodaresi Z. Treatment of strip perforation using cold ceramic. Dent Res J (Isfahan). 2023;20:31.
24. Demirci M, Tuncer S, Yuceokur AA. Prevalence of caries on individual tooth surfaces and its distribution by age and gender in university clinic patients. Eur J Dent. 2010;4:270-9.
25. Vertucci, F. J. (2005). Root canal morphology and its relationship to endodontic procedures. Endodontic Topics, 10(1), 3-29.
26. Torabinejad, M., Corr, R., Handysides, R., & Shabahang, S. (2009). Outcomes of nonsurgical retreatment and endodontic surgery: a systematic review. Journal of Endodontics, 35(7), 930-937.
27. Quality guidelines for endodontic treatment: consensus report of the European Society of Endodontology. Int Endod J. 2006;39:921-30.
28. Mozayeni MA, Salem Milani A, Alim Marvasti L, Mashadi Abbas F, Modaresi SJ. Cytotoxicity of Cold Ceramic Compared with MTA and IRM. Iran Endod J. 2009;4:106-11.
29. Khalil I, Isaac J, Chaccar C, Sautier JM, Berdal A, Naaman N, et al. Biocompatibility assessment of modified Portland cement in comparison with MTA®: In vivo: and: in vitro: studies. Saudi Endod J. 2012;2:6-13.
30. Saad AY. Physicochemical, cytotoxicity, and biological properties of calcium silicate-based root canal sealers: A literature review. Saudi Endod J. 2020;10:173-80.
2. Torabinejad M, Watson TF, Pitt Ford TR. Sealing ability of a mineral trioxide aggregate when used as a root end filling material. J Endod. 1993;19(12):591-595.
3. Parirokh M, Torabinejad M. Mineral trioxide aggregate: a comprehensive literature review—Part I: chemical, physical, and antibacterial properties. J Endod. 2010;36(1):16-27.
4. Parirokh M, Torabinejad M. Mineral trioxide aggregate: a comprehensive literature review—Part II: leakage and biocompatibility investigations. J Endod. 2010;36(2):190-202.
5. Modaresi J, Parirokh M, Asgary S. Evaluation of the sealing ability of a new endodontic cement (Cold Ceramic) as root-end filling material. J Endod. 2005;31(2):102-105.
6. Asgary S, Eghbal MJ, Parirokh M, Ghoddusi J, Kheirieh S, Brink F. Comparison of mineral trioxide aggregate’s composition with Portland cements and a new endodontic cement. J Endod. 2009;35(2):243-250.
7. Asgary S, Eghbal MJ, Parirokh M, Ghoddusi J, Kheirieh S, Brink F. A comparative study of the effect of Cold Ceramic and MTA on the healing of furcation perforations in dogs. J Endod. 2008;34(8):923-927.
8. Modaresi J, Asgary S. Cold Ceramic: A new endodontic filling material. Iran Endod J. 2006;1(1):1-5.
9. Modaresi J, Khademi A, Hemati H, Mokhtari F. Histological evaluation of ProRoot mineral trioxide aggregate and Cold ceramic as root-end filling materials in animal models. Dent Res J (Isfahan). 2023;20:58.
10. Khedmat S, Sarraf P, Seyedjafari E, Sanaei-Rad P, Noori F. Comparative evaluation of the effect of cold ceramic and MTA-Angelus on cell viability, attachment and differentiation of dental pulp stem cells and periodontal ligament fibroblasts: an in vitro study. BMC Oral Health. 2021;21:628.
11. Mokhtari F, Modaresi J, Javadi G, Davoudi A, Badrian H. Comparing the Marginal Adaptation of Cold Ceramic and Mineral Trioxide Aggregate by Means of Scanning Electron Microscope: An In vitro Study. J Int Oral Health. 2015;7:7-10.
12. Modaresi J, Yavari SA, Dianat SO, Shahrabi S. A comparison of tissue reaction to MTA and an experimental root-end restorative material in rats. Aust Endod J. 2005;31:69-72.
13. Akhavan A, Parashos P, Razavi SM, Davoudi A, Shadmehr E. Hard tissue reaction to mineral trioxide aggregate and experimental root-end filling material in guinea pig mandibles. J Dent Sci. 2017;12:107-11.
14. Rasteh B, Basir L, Taravati S, Khataminia M. Evaluation and comparison of mineral trioxide aggregate and cold ceramic in primary tooth pulpotomy: Clinical and radiographic study. J Family Med Prim Care. 2023;12:3068-74.
15. Modaresi J, Nasr N. Nonsurgical Endodontic Management of Large Periapical Lesion with Cold Ceramic: A Literature Review and Case Series. Iran Endod J. 2023;18:113-21.
16. Modaresi J, Mirzaeeian A, Almodaresi Z, Mousavi R. Apexification of an Immature Tooth with Cold Ceramic: A Case Report. J Isfahan Dent Sch. 2020;16:345-51.
17. Marzoughi Shirin, Salari Moghaddam Reza, Faghihian Reyhaneh, MORADI SAMANEH, SOLTANI MEHDI. Apexification of an Immature Permanent First Molar Tooth with Cold Ceramic: A Case Report. JOURNAL OF ISFAHAN DENTAL SCHOOL[Internet]. 2022;17(4 ):467-473.
18. AYATOLLAHI FATEMEH, Zahedinejad Amirali, Bagheri Hariri Aida, MODARESI JALIL. A case report of successful apexification in mandibular second molar, using cold ceramics”,. JOURNAL OF RESEARCH IN DENTAL SCIENCES[Internet]. 2023;20(1 (75) ):70-75.
19. Ghabraei S, Bolhari B, Hashemi N, Gharehchahi H. Conservative management of an advanced external cervical resorption with internal approach using bio-ceramic materials: A case report. Clin Case Rep. 2024;12:e8378.
20. Modaresi J, Almodaresi z, Mousavi R, Mirzaeeian A. Successful Root Canal Treatment with Cold Ceramic: A Case Report. J Mashhad Dent Sch. 2021;45:309-13.
21. ModaresiJ,Yazdani RostamA,MahiniF,NasrN.ColdCeramicasaRootCanalFillingMaterial:ACaseSeries.JDentSch2024;42(1):49-55.
22. Modaresi J, Almodaresi Z, Mousavi R, Mirzaeeian A, Hosseini SAS. Successful management of a tooth with canal obstruction using "cold ceramic". Dent Res J (Isfahan). 2021;18:77.
23. Modaresi J, Parashos P, Mousavi R, Mirzaeeian A, Almodaresi Z. Treatment of strip perforation using cold ceramic. Dent Res J (Isfahan). 2023;20:31.
24. Demirci M, Tuncer S, Yuceokur AA. Prevalence of caries on individual tooth surfaces and its distribution by age and gender in university clinic patients. Eur J Dent. 2010;4:270-9.
25. Vertucci, F. J. (2005). Root canal morphology and its relationship to endodontic procedures. Endodontic Topics, 10(1), 3-29.
26. Torabinejad, M., Corr, R., Handysides, R., & Shabahang, S. (2009). Outcomes of nonsurgical retreatment and endodontic surgery: a systematic review. Journal of Endodontics, 35(7), 930-937.
27. Quality guidelines for endodontic treatment: consensus report of the European Society of Endodontology. Int Endod J. 2006;39:921-30.
28. Mozayeni MA, Salem Milani A, Alim Marvasti L, Mashadi Abbas F, Modaresi SJ. Cytotoxicity of Cold Ceramic Compared with MTA and IRM. Iran Endod J. 2009;4:106-11.
29. Khalil I, Isaac J, Chaccar C, Sautier JM, Berdal A, Naaman N, et al. Biocompatibility assessment of modified Portland cement in comparison with MTA®: In vivo: and: in vitro: studies. Saudi Endod J. 2012;2:6-13.
30. Saad AY. Physicochemical, cytotoxicity, and biological properties of calcium silicate-based root canal sealers: A literature review. Saudi Endod J. 2020;10:173-80.
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Issue | Vol 11, No 3 (Summer 2024) | |
Section | Review Article(s) | |
Keywords | ||
Apexification; Biocompatibility; Case report; Cold ceramic; Endodontics; Root canal; Root perforation; Sealing ability; Treatment. |
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
How to Cite
1.
Roshani A, Hashemi Baraz SA, Shiezadeh I. Cold Ceramic in Endodontics Treatments: A Review. J Craniomaxillofac Res. 2024;11(3):146-154.