Developing Complex Odontome–an Enigmatic Entity: A Case Report
Abstract
A benign mixed odontogenic lesion, with features of ameloblastic fibro odontoma previously allocated in the WHO 2005 classification, and presently removed in the subsequent WHO 2017 and 2022 classifications, shows certain changes that result in the formation of enamel and dentin, suggestive of a developing complex odontoma rather than ameloblastic fibro odontoma. It commonly affects individuals in the first and second decades of life. The present case exhibits histopathological features which show enamel and dentin formation and strands of ameloblast-like cells with an inductive process. The histopathology points to a hallmark diagnosis of a “developing” complex odontoma. Keywords: WHO; Odontogenic; Inductive changes; Ameloblast.
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2. Wright JM, Soluk Tekkesin M. Odontogenic tumors: where are we in 2017 ?. J Istanb Univ Fac Dent. 2017;51(3 Suppl 1):S10-S30. Published 2017 Dec 2. doi:10.17096/jiufd.52886
3. Peter A. Reichart, Hans P. Philipsen Odontogenic, Tumors and Allied Lesions, 1st edition, Quintessence Publishing Co Ltd.
4. Soluk-Tekkesin M, Vered M. Ameloblastic Fibro-Odontoma: At the Crossroad Between "Developing Odontoma" and True Odontogenic Tumour. Head Neck Pathol. 2021;15(4):1202-1211. doi:10.1007/s12105-021-01332-6.
5. Robert M. Howell, E.Jefferson Burkes,Malignant transformation of ameloblastic fibro-odontoma to ameloblastic fibrosarcoma,Oral Surgery, Oral Medicine, Oral Pathology,Volume 43, Issue 3,1977
6. Gomes, IP, Bastos, VC, Guimaraes, LM, Gomes, CC. The molecular basis of odontogenic cysts and tumours. J Oral Pathol Med. 2023; 52(4): 351-356.
7. Ian Furst, Michael Pharoah, John Phillips, Recurrence of an ameloblastic fibro-odontoma in a 9-year-old boy, Journal of Oral and Maxillofacial Surgery, Volume 57, Issue 5,1999.
8. Maltagliati, Alberto & Ugolini, Alessandro & Crippa, Rolando & Farronato, Marco & Paglia, Michela & Blasi, Sergio & Angiero, Francesca. (2020). Complex odontoma at the upper right maxilla: Surgical management and histomorphological profile. European Journal of Paediatric Dentistry. 21. 199. 10.23804/ejpd.2020.21.03.08.
9. Sanjai, Karpagaselvi et al. “Ameloblastic Fibro-Odontoma: A Journey of Progression?.” Journal of oral and maxillofacial pathology : JOMFP vol. 26,Suppl 1 (2022): S40-S45.
10. O’Brien FV. Ameloblastic odontome. A case report. British Dental Journal. 1971;131(2):71–72.
11. Wu PC, Chan KW. A survey of tumours of the jawbones in Hong Kong Chinese: 1963–1982. British Journal of Oral and Maxillofacial Surgery. 1985;23(2):92–102.
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Issue | Vol 12, No 2 (Spring 2025) | |
Section | Case Report(s) | |
Keywords | ||
WHO dontogenic Inductive changes Ameloblast |
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How to Cite
1.
Harika Varshita B, Uppala D, Kotina S, Raviteja Y, Balla H, Sreevalli U. Developing Complex Odontome–an Enigmatic Entity: A Case Report. J Craniomaxillofac Res. 2025;12(2):129-133.