Oral Mandibular Peripheral Osteoma: A Case Report
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Abstract
Peripheral osteomas of the mandible are rare, benign osteogenic tumors characterized by slow-growing cortical or cancellous bone proliferation. This report presents a case of a peripheral osteoma in the mandibular angle and reviews potential etiological factors. A 72-year-old woman presented with a painless, asymptomatic mandibular bone asymmetry and was referred to the oral and maxillofacial department of Isfahan University of Medical Sciences with no visible asymmetric changes in facial soft tissue. The lesion was a 4 cm pedunculated radiopaque mass located on the buccal surface of the left posterior mandible, as confirmed by computed tomography. Surgical excision revealed histopathological features characteristic of lamellar bone admixed with some woven bone, consistent with a diagnosis of peripheral osteoma. Postoperative recovery was smooth, and there was no evidence of recurrence at 1-year follow-up. Peripheral osteomas frequently occur in the mandible and can lead to functional disruptions or cosmetic concerns. Trauma and chronic muscle tension can contribute to their formation, but many cases arise without a clear cause. Typically asymptomatic, surgical removal is the most effective treatment with low recurrence rates. A thorough radiographic assessment is essential; more research is needed to understand their molecular mechanisms. Keywords: Peripheral osteoma; Mandible; Benign bone tumor; Case report; Risk factors.
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[32]. y Baena RR, Rizzo S, Fiandrino G, Lupi S, Galioto S. Mandibular traumatic peripheral osteoma: a case report. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 2011;112(6):e44-e8.
[33]. D’Agostino S, Dell’Olio F, Tempesta A, Cervinara F, D’Amati A, Dolci M, et al. Osteoma of the jaw as first clinical sign of Gardner’s syndrome: the experience of two Italian centers and review. Journal of clinical medicine. 2023;12(4):1496.
[34]. Johann ACBR, de Freitas JB, de Aguiar MCF, de Araújo NS, Mesquita RA. Peripheral osteoma of the mandible: case report and review of the literature. Journal of Cranio-Maxillofacial Surgery. 2005;33(4):276-81.
[35]. Ostrofsky M, Morkel J, Titinchi F. Osteoma of the mandibular condyle: a rare case report and review of the literature. Journal of stomatology, oral and maxillofacial surgery. 2019;120(6):584-7.
[36]. Sayan NB, Üçok C, Karasu HA, Günhan Ö. Peripheral osteoma of the oral and maxillofacial region: a study of 35 new cases. Journal of Oral and Maxillofacial Surgery. 2002;60(11):1299-301.
[37]. Chattopadhyay CP, Chander MGM. Peripheral osteoma of the maxillofacial region diagnosis and management: a study of 06 cases. Journal of maxillofacial and oral surgery. 2012;11:425-9.
[2]. Gümüşok M, Değerli Ş, Toprak M, Seçkin A, Kaya E, Şengüven B. Peripheral osteoma of the mandible: a case report. Journal of Istanbul University Faculty of Dentistry. 2015;49(1):47-50.
[3]. Nakayama A, Abe R, Takahashi M, Yamada H, Takeda Y. Peripheral osteoma in an unusual region of the mandible: A case report. Oral and Maxillofacial Surgery Cases. 2021;7(1):100207.
[4]. Manekar VS, Dewalwar V. Solitary peripheral osteoma of the mandible presented as trismus. International Journal of Head and Neck Surgery. 2016;5(3):161-4.
[5]. Agrawal R, Agrawal S, Bhargava S, Motlani M, Agrawal R. An uncommon case of solitary peripheral osteoma in the mandible. Case Reports in Dentistry. 2015;2015(1):319738.
[6]. Almeida LE, de Oliveira Filho MA. Giant mandibular condyle osteoma. Journal of Craniofacial Surgery. 2011;22(3):1147-9.
[7]. Woldenberg Y, Nash M, Bodner L. Peripheral osteoma of the maxillofacial region. Diagnosis and management: a study of 14 cases. Med Oral Patol Oral Cir Bucal. 2005;10(Suppl 2):E139-42.
[8]. Geron ABG, Carvalho VA, Dos Santos JL, Almeida LY, León JE, Trivellato AE, et al. Surgical management of traumatic peripheral osteoma of the mandible. Journal of Craniofacial Surgery. 2017;28(4):e405-e8.
[9]. Kaplan I, Nicolaou Z, Hatuel D, Calderon S. Solitary central osteoma of the jaws: a diagnostic dilemma. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 2008;106(3):e22-e9.
[10]. Kerckhaert A, Wolvius E, Van Der Wal K, Oosterhuis JW. A giant osteoma of the mandible: case report. Journal of Cranio-Maxillofacial Surgery. 2005;33(4):282-5.
[11]. Neville BW, Damm DD, Allen CM, Chi AC. Bone Pathology. Oral and maxillofacial pathology. Fifth edition ed: Elsevier Health Sciences; 2023. p. 655-6.
[12]. Arslan HH, Tasli H, Cebeci S, Gerek M. The management of the paranasal sinus osteomas. Journal of Craniofacial Surgery. 2017;28(3):741-5.
[13]. Bhatt G, Gupta S, Ghosh S, Mohanty S, Kumar P. Central osteoma of maxilla associated with an impacted tooth: report of a rare case with literature review. Head and Neck Pathology. 2019;13:554-61.
[14]. Orabona GDA, Salzano G, Iaconetta G, Piombino P, Ponzo L, Santella A, et al. Facial osteomas: fourteen cases and a review of literature. Eur Rev Med Pharmacol Sci. 2015;19(10):1796-802.
[15]. Ghita I, Brooks JK, Bordener SL, Emmerling MR, Price JB, Younis RH. Central compact osteoma of the mandible: case report featuring unusual radiographic and computed tomographic presentations and brief literature review. Journal of Stomatology, Oral and Maxillofacial Surgery. 2021;122(5):516-20.
[16]. Halawi AM, Maley JE, Robinson RA, Swenson C, Graham SM. Craniofacial osteoma: clinical presentation and patterns of growth. American journal of rhinology & allergy. 2013;27(2):128-33.
[17]. Herford AS, Stoffella E, Tandon R. Osteomas involving the facial skeleton: a report of 2 cases and review of the literature. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 2013;115(2):e1-e6.
[18]. Larrea‐Oyarbide N, Valmaseda‐Castellón E, Berini‐Aytés L, Gay‐Escoda C. Osteomas of the craniofacial region. Review of 106 cases. Journal of oral pathology & medicine. 2008;37(1):38-42.
[19]. McHugh JB, Mukherji SK, Lucas DR. Sino-orbital osteoma: a clinicopathologic study of 45 surgically treated cases with emphasis on tumors with osteoblastoma-like features. Archives of pathology & laboratory medicine. 2009;133(10):1587-93.
[20]. Bulut E, Acikgoz A, Ozan B, Gunhan O. Large peripheral osteoma of the mandible: a case report. International journal of dentistry. 2010;2010(1):834761.
[21]. Ozturk H, Torul D, Yuceer E, Karli R, Baris S. Peripheral osteoma of mandibular angulus: analysis of the literature and report of a new case. Odovtos-International Journal of Dental Sciences. 2018;20(2):61-70.
[22]. Maksoud C, Akouri E, Chammas C, Aoun G, Akouri EE. Peripheral osteoma: a report of a case in the Anterior Mandibular Region. Cureus. 2023;15(11).
[23]. Karandikar S, Thakur G, Tijare M, Agrawal K. Osteoid osteoma of mandible. Case Reports. 2011;2011:bcr1020114886.
[24]. Nayak V, Rao PK, Kini R, Shetty U. Peripheral osteoma of the mandible. BMJ Case Reports. 2020;13(9):e238225.
[25]. Horikawa FK, de Freitas RR, Maciel FA, Gonçalves AJ. Peripheral osteoma of the maxillofacial region: a study of 10 cases. Brazilian journal of otorhinolaryngology. 2012;78(5):38-43.
[26]. Durão AR, Chilvarquer I, Hayek JE, Provenzano M, Kendall MR. Osteoma of the zygomatic arch and mandible: report of two cases. Revista Portuguesa de Estomatologia, Medicina Dentária e Cirurgia Maxilofacial. 2012;53(2):103-7.
[27]. Tilaveridis I, Katopodi T, Karakostas P, Venetis G, Dimitrakopoulos I, Tilaveridis S, et al. Peripheral osteoma of the mandibular condyle—case series. Dentistry Journal. 2022;10(10):182.
[28]. Soni S, Bhargava A. Revisiting peripheral osteoma of the mandible with case series and review of literature. Indian Journal of Otolaryngology and Head & Neck Surgery. 2014;66:212-8.
[29]. Tarsitano A, Ricotta F, Spinnato P, Chiesa AM, Di Carlo M, Parmeggiani A, et al. Craniofacial osteomas: from diagnosis to therapy. Journal of clinical medicine. 2021;10(23):5584.
[30]. Hasan S. Giant osteoma of the mandible: report of a rare case with review of literature. Indian Journal of Otolaryngology and Head & Neck Surgery. 2022:1-8.
[31]. Matthies L, Rolvien T, Pakusa TJ, Knipfer C, Gosau M, Amling M, et al. Osteoid osteoma of the mandible–clinical and histological findings. Anticancer Research. 2019;39(1):291-6.
[32]. y Baena RR, Rizzo S, Fiandrino G, Lupi S, Galioto S. Mandibular traumatic peripheral osteoma: a case report. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 2011;112(6):e44-e8.
[33]. D’Agostino S, Dell’Olio F, Tempesta A, Cervinara F, D’Amati A, Dolci M, et al. Osteoma of the jaw as first clinical sign of Gardner’s syndrome: the experience of two Italian centers and review. Journal of clinical medicine. 2023;12(4):1496.
[34]. Johann ACBR, de Freitas JB, de Aguiar MCF, de Araújo NS, Mesquita RA. Peripheral osteoma of the mandible: case report and review of the literature. Journal of Cranio-Maxillofacial Surgery. 2005;33(4):276-81.
[35]. Ostrofsky M, Morkel J, Titinchi F. Osteoma of the mandibular condyle: a rare case report and review of the literature. Journal of stomatology, oral and maxillofacial surgery. 2019;120(6):584-7.
[36]. Sayan NB, Üçok C, Karasu HA, Günhan Ö. Peripheral osteoma of the oral and maxillofacial region: a study of 35 new cases. Journal of Oral and Maxillofacial Surgery. 2002;60(11):1299-301.
[37]. Chattopadhyay CP, Chander MGM. Peripheral osteoma of the maxillofacial region diagnosis and management: a study of 06 cases. Journal of maxillofacial and oral surgery. 2012;11:425-9.
| Files | ||
| Issue | Vol 13, No 1 (Winter 2026) | |
| Section | Case Report(s) | |
| Keywords | ||
| Peripheral osteoma; Mandible; Benign bone tumor; Case report; Risk factors. | ||
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How to Cite
1.
Khozeimeh F, Karami F, Amirzade-Iranaq MH, Ahmadi S. Oral Mandibular Peripheral Osteoma: A Case Report. J Craniomaxillofac Res. 2026;13(1):134-140.
