Oral and dental complications caused by methamphetamine use: A review
AbstractBackground and Objectives: Methamphetamine is a stimulant drug with stimulatory effects on the central nervous system. It also negatively affects the oral and dental health. This narrative review aims to review the oral and dental complications caused by methamphetamine use.Materials and Methods: In this narrative review, an electronic search of the literature was carried out in Google Scholar, PubMed and SID databases for original articles published from 2000 to 2017 using the keywords “meth”, “mouth”, “methamphetamine”, “dental caries”, “oral health” and “dental problem”.Results: The most prevalent complications caused by methamphetamine use were xerostomia (94%), bad taste in the mouth (91%), extensive caries (89%), facial muscle stiffness (73%), dental esthetic problems (68%) and increased acidity of the saliva (68%). Temporomandibular joint problem had the lowest prevalence (13%).Conclusion: Long-term methamphetamine use causes adverse oral and dental changes. By having adequate knowledge about the prevalence and physiopathology of these complications, clinicians can promote oral and dental health and decrease treatment costs.Keywords: Methamphetamine, Dental Caries, Bruxism, Meth Mouth, Gingival Inflammation.
Ravenel, M.C., et al., Methamphetamine abuse and oral health: A pilot study of" meth mouth". Quintessence international, 2012. 43. (3).
Maxwell, J.C., et al., The prevalence of methamphetamine and amphetamine abuse in North America: a review of the indicators, 1992–2007. Drug Alcohol Rev 2008. 27(3): p. 229-235.
Shetty, V., et al., The relationship between methamphetamine use and increased dental disease. J Am Dent Assoc, 2010. 141(3): p. 307-318.
Comer, S.D., et al., Effects of repeated oral methamphetamine administration in humans. Psychopharmacology, 2001. 155(4).
Saini, T.S., et al., Etiology of xerostomia and dental caries among methamphetamine abusers. Oral health Prev Dent, 2005. 3(3).
Shaner, J.W., et al., " Meth mouth": rampant caries in methamphetamine abusers. AIDS Patient Care & STDs, 2006. 20(3): p. 146-150.
Hamamoto, D. and N. Rhodus, Methamphetamine abuse and dentistry. Oral diseases, 2009. 15(1): p. 27-37.
Durell, T.M., et al., Prevalence of nonmedical methamphetamine use in the United States. Substance abuse treatment, prevention, and policy, 2008. 3(1): p. 19.
Schramm, W., et al., Drugs of abuse in saliva: a review. J Anal Toxicol, 1992. 16(1): p. 1-
Kidwell, D.A., J.C. Holland, and S. Athanaselis, Testing for drugs of abuse in saliva and sweat. Journal of Chromatography B: Biomedical Sciences and Applications, 1998. 713(1): p. 111-135.
Klasser, G.D. and J. Epstein, Methamphetamine and its impact on dental care. J Can Dent Assoc, 2005. 71(10): p. 759-62.
Shaner, J.W., Caries associated with methamphetamine abuse. J Dent Mich Assoc, 2002. 84(9): p. 42-47.
McGrath, C. and B. Chan, Oral health sensations associated with illicit drug abuse. Br Dent J, 2005. 198(3): p. 159-162.
Richards, J.R. and B.T. Brofeldt, Patterns of tooth wear associated with methamphetamine use. J Periodontol, 2000. 71(8): p. 1371-1374.
Lindsay, B., J. Albrecht, and M. Terplan, Against professional advice: treatment attrition among pregnant methamphetamine users. Substance abuse and rehabilitation, 2011. 2: p. 189.
Chen, W.-H., et al., A proposed mechanism for diurnal/nocturnal bruxism: hypersensitivity of presynaptic dopamine receptors in the frontal lobe. J Clin Neurosci, 2005. 12(2): p. 161-163.
Arrue, A., F.M. Gómez, and M.T. Giralt, Effects of 3, 4‐methylenedioxymethamphetamine (‘Ecstasy’) on the jaw‐opening reflex and on the α2‐adrenoceptors which regulate this reflex in the anesthetized rat. Eur J Oral Sci, 2004. 112(2): p. 127-133.
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