Solitary Intraosseous Neurofibroma Of Mandible: A Case Report
Abstract
Neurofibroma is a benign tumor derived from the peripheral nerve. Most of these can be multifocal as a component of neurofibromatosis or present as a solitary tumor. Although the solitary neurofibroma is not an uncommon lesion, its intraosseous occurrence is rare, and less than 50 cases have been reported. We report a rare case of central neurofibroma, arising in the mandibular bone of 57-year-old edentulous female patient on the left side. Hemi mandibulectomy was performed and reconstructed with a reconstruction plate without any bone graft. Microscopic evaluation showed neoplastic tissue with haphazardly arranged and interlacing fascicular patterns composed of point-ended spindle-shaped tumoral cells. Immunohistochemical examination of the tumor showed positive staining for S-100 protein antibodies.Keywords: Intraosseous neurofibroma; Mandible.
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8. Zhang Z, Hong X, Wang F, et al. Solitary intraosseous neurofibroma in the mandible mimicking a cystic lesion: A case report and review of literature. World J Clin Cases. 2023;11(27):6653-6663. doi:10.12998/wjcc.v11.i27.6653
9. Deichler J, Martínez R, Niklander S, et al. Solitary intraosseous neurofibroma of the mandible. Apropos of a case. Med Oral Patol Oral Cir Bucal 2011;16:e704-7.
10. Apostolidis C, Anterriotis D, Rapidis AD, et al. Solitary intraosseous neurofibroma of the inferior alveolar nerve: report of a case. J Oral Maxillofac Surg 2001;59:232-5.
11. Jangam SS, Ingole SN, Deshpande MD, et al. Solitary intraosseous neurofibroma: Report of a unique case. Contemp Clin Dent 2014;5:561-3.
12. Sharma P, Shah SV, Patel AM, et al. Primary intraosseous carcinoma with nodal metastasis masquerading as ameloblastom-a rare case report. Indian J Surg Oncol 2011;2:148-50.
13. Vivek N, Manikandhan R, James PC, et al. Solitary intraosseous neurofibroma of mandible. Indian J Dent Res 2006;17:135-8.
14. Huang GS, Lee CH, Lee HS, et al. Solitary intraosseous neurofibroma of the tibia. Skeletal Radiol 2005;34:303-6.
15. Gómez-Oliveira G, Fernández-Alba Luengo J, Martín-Sastre R, et al. Plexiform neurofibroma of the cheek mucosa. A case report. Med Oral 2004;9:263-7.
16. Gnepp DR, Keyes GG. Central neurofibromas of the mandible: report of two cases. J Oral Surg 1981;39:125-7.
17. Misra S, Gogri P, Misra N, Bhandari A. Recurrent neurofibroma of the orbit. Australas Med J 2013;6:189-91.
18. Mori H, Kakuta S, Yamaguchi A, et al. Solitary intraosseous neurofibroma of the maxilla: report of a case. J Oral Maxillofac Surg 1993;51:688-90.
19. Poupard RJ, Mintz S. Solitary intrabony neurofibroma of the maxilla. J Oral Maxillofac Surg 1997;55:768-72.
2. Ide F, Shimoyama T, Horie N, et al. Comparative ultrastructural and immunohistochemical study of perineurioma and neurofibroma of the oral mucosa. Oral Oncol 2004;40:948-53.
3. Neville BW, Damm DD, Chi AC, Allen CM. Oral and maxillofacial pathology. 3rd ed. Elsevier Health Sciences; 2009; p.p: xvi, 968.
4. Toth BB, Long WH, Pleasants JE. Central pacinian neurofibroma of the maxilla. Oral Surg Oral Med Oral Pathol 1975;39:630-4.
5. Polak M, Polak G, Brocheriou C, et al. Solitary neurofibroma of the mandible: case report and review of the literature. J Oral Maxillofac Surg 1989;47:65-8.
6. BRUCE KW. Solitary neurofibroma (neurilemmoma, schwannoma) of the oral cavity. Oral Surg Oral Med Oral Pathol 1954;7:1150-9.
7. Dalili Z, Adham G. Intraosseous neurofibroma and concurrent involvement of the mandible, maxilla and orbit: report of a case. Iran J Radiol 2012;9:45-9.
8. Zhang Z, Hong X, Wang F, et al. Solitary intraosseous neurofibroma in the mandible mimicking a cystic lesion: A case report and review of literature. World J Clin Cases. 2023;11(27):6653-6663. doi:10.12998/wjcc.v11.i27.6653
9. Deichler J, Martínez R, Niklander S, et al. Solitary intraosseous neurofibroma of the mandible. Apropos of a case. Med Oral Patol Oral Cir Bucal 2011;16:e704-7.
10. Apostolidis C, Anterriotis D, Rapidis AD, et al. Solitary intraosseous neurofibroma of the inferior alveolar nerve: report of a case. J Oral Maxillofac Surg 2001;59:232-5.
11. Jangam SS, Ingole SN, Deshpande MD, et al. Solitary intraosseous neurofibroma: Report of a unique case. Contemp Clin Dent 2014;5:561-3.
12. Sharma P, Shah SV, Patel AM, et al. Primary intraosseous carcinoma with nodal metastasis masquerading as ameloblastom-a rare case report. Indian J Surg Oncol 2011;2:148-50.
13. Vivek N, Manikandhan R, James PC, et al. Solitary intraosseous neurofibroma of mandible. Indian J Dent Res 2006;17:135-8.
14. Huang GS, Lee CH, Lee HS, et al. Solitary intraosseous neurofibroma of the tibia. Skeletal Radiol 2005;34:303-6.
15. Gómez-Oliveira G, Fernández-Alba Luengo J, Martín-Sastre R, et al. Plexiform neurofibroma of the cheek mucosa. A case report. Med Oral 2004;9:263-7.
16. Gnepp DR, Keyes GG. Central neurofibromas of the mandible: report of two cases. J Oral Surg 1981;39:125-7.
17. Misra S, Gogri P, Misra N, Bhandari A. Recurrent neurofibroma of the orbit. Australas Med J 2013;6:189-91.
18. Mori H, Kakuta S, Yamaguchi A, et al. Solitary intraosseous neurofibroma of the maxilla: report of a case. J Oral Maxillofac Surg 1993;51:688-90.
19. Poupard RJ, Mintz S. Solitary intrabony neurofibroma of the maxilla. J Oral Maxillofac Surg 1997;55:768-72.
| Files | ||
| Issue | Vol 10, No 4 (Autumn 2023) | |
| Section | Case Report(s) | |
| DOI | https://doi.org/10.18502/jcr.v10i4.15314 | |
| Keywords | ||
| Intraosseous neurofibroma Mandib | ||
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How to Cite
1.
Abbasi A, Aminishakib P, Arashrad M. Solitary Intraosseous Neurofibroma Of Mandible: A Case Report. J Craniomaxillofac Res. 2024;10(4):208-211.
