Crohnʼs Disease with Gingival Enlargement as the First Sign: A Case Report
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Abstract
Crohn’s disease (CD) is a process of gastrointestinal mucosa inflammation that could be seen in any part of the gastrointestinal tract from oral to anus. Oral lesions could be the first sign in most patients. The lesions in Crohn’s disease are divided to specific and nonspecific lesions. The specific lesions are less common than nonspecific ones. Tag-like lesions and cobblestones are some of the specific lesions and ulcer is a non-specific lesion. The diagnosis of Crohn’s disease is based on a combination of symptoms, enteroscopy, gastroscopy, capsule endoscopy, histopathology and imaging. Oral involvement of CD is also known as oral Crohn’s disease (OCD). Early diagnosis of OCD may be the most influential factor in controlling it. This case report presents a 47-year-old female patient with gingivitis and gingival erythema and enlargement as her chief complaint which was the first sign of CD. Keywords: Pathology; Oral; Crohn’s disease; Gingival enlargement.
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2. Padmavathi B, Sharma S, Astekar M, Rajan Y, Sowmya G. Oral Crohn's disease. J Oral Maxillofac Pathol 2014; 18(Suppl 1): S139-42.
3. Alrashdan MS, Safadi RA. Crohn's disease initially presenting with oral manifestations and managed with ustekinumab: A case report. Spec Care Dentist. 2021; 41(5): 634-8.
4. Lauritano D, Boccalari E, Di Stasio D, Della Vella F, Carinci F, Lucchese A, Petruzzi M. Prevalence of oral lesions and correlation with intestinal symptoms of inflammatory bowel disease: a systematic review. Diagnostics (Basel). 2019, 9.
5. Lauritano D, Boccalari E, Di Stasio D, Della Vella F, Carinci F, Lucchese A, et al. Prevalence of oral lesions and correlation with intestinal symptoms of inflammatory bowel disease: a systematic review. Diagnostics (Basel) 2019; 9(3): 77.
6. Muhvić-Urek M, Tomac-Stojmenović M, Mijandrušić-Sinčić B. Oral pathology in inflammatory bowel disease. World J Gastroenterol 2016; 22(25): 5655-67.
7. Ribaldone DG, Brigo S, Mangia M, Saracco GM, Astegiano M, Pellicano R. Oral manifestations of inflammatory bowel disease and the role of non-invasive surrogate markers of disease activity. Medicines (Basel) 2020; 7(6): 33.
8. Tan CXW, de Boer NKH, Brand HS. Orale manifestaties van de ziekte van Crohn [Oral manifestations of Crohn's disease]. Ned Tijdschr Tandheelkd 2018; 125(1): 15-20.
9. Sbeit W, Kadah A, Mahamid M, Karayanni H, Mari A, Tali S, et al. Oral manifestations of inflammatory bowel disease: the neglected piece of the puzzle. Eur J Gastroenterol Hepatol 2020; 32(11): 1422-31.
10. Campbell H, Escudier M, Patel P, Nunes C, Elliott TR, Barnard K, et al. Distinguishing orofacial granulomatosis from crohn's disease: two separate disease entities? Inflamm Bowel Dis 2011; 17(10): 2109-15.
11. Lankarani KB, Sivandzadeh GR, Hassanpour S. Oral manifestation in inflammatory bowel disease: a review. World J. Gastroenterol. 2013; 19: 8571–8579.
12. Laube R, Liu K, Schifter M, Yang JL, Suen MK, Leong RW. Oral and upper gastrointestinal Crohn's disease. J Gastroenterol Hepatol 2018; 33(2): 355-64.
13. Katsanos KH, Torres J, Roda G, Brygo A, Delaporte E, Colombel JF. Review article: non-malignant oral manifestations in inflammatory bowel diseases. Aliment Pharmacol Ther 2015; 42(1): 40-60.
14. Iqbal F, Schifter M, Coleman HG. Oral presentation of histoplasmosis in an immunocompetent patient: a diagnostic challenge. Aust Dent J 2014; 59(3): 386-8.
15. Alawi F. Granulomatous diseases of the oral tissues: differential diagnosis and update. Dent Clin North Am 2005; 49(1): 203-21.
| Files | ||
| Issue | Vol 11, No 2 (Spring 2024) | |
| Section | Case Report(s) | |
| Keywords | ||
| Pathology; Oral; Crohn’s disease; Gingival enlargement. | ||
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
How to Cite
1.
Fattahi B, Khalesi S, Badi Sanaye MR, Momeni AM. Crohnʼs Disease with Gingival Enlargement as the First Sign: A Case Report. J Craniomaxillofac Res. 2024;11(2):133-137.
