Pleomorphic Adenoma in Palatal Region of a Young Patient: A Case Report
Abstract
Pleomorphic adenoma is the most common benign tumor of the salivary glands. Its gender tendency is in females and mostly in the age of 20-45 years. mixed tumor has a firm consistency and no bone involvement. The mocusal memberan on it is healthy and has a normal color. It grows slowly and expands slowly.The parotid region, as the major salivary gland and the minor salivary gland, especially the palatal is the main site of this lesion. Cases of malignant changes have been found in it and it can turn into carcinoma. The patient is an 11-year-old girl without any underlying disease who referred to the outpatient clinic of Maxillofacial Surgery in Bahonar Kerman Hospital in Iran. The patient complained of a swelling in the left plat region, which he said had started about three months ago and was getting bigger. In examining the consistency of the lesion, it was firm and its color was pink like the mucosa of the normal palate. The uniformity of the mucosa was preserved on it. The dimensions of the lesion were about 3 x 2.5 square centimeters. The patient did not express pain or discomfort. First, a panoramic radiograph (OPG) was prepared. And then CBCT images were prepared with one millimeter slices. In the examination of the lesion, expansion is seen along with specific limits of the borders. The lesion did not destroy the palatine bone and did not invade the maxillary sinus. No pus drainage, inflammation, or redness was evident in the examination, and tenderness was not reported by the patient.then she refered to the endodontics part for examination of vitality tests. All of the teeth were vital. After performing diagnostic work, the patient was prepared for biopsy and enucleation and curettage of the lesion. After explaining to the patient and his parents and obtaining informed consent for the treatment and surgery. At first aspiration was done and the result was negative, then a sulcular incision was made from the area of the 4th upper right tooth to the 7th upper left mesial. After dissection, the mass was completely removed and enucleated. The mucosa of the floor of the nose remained healthy, and the area was completely curettage with a curet while maintaining the health of the nasal mucosa. Soft tissue sutured with 0-4 vicryl. Then, she underwent periodical follow-ups and the sample was sent for pathology examination. And the answer was diagnosed by seeing epithelial and myoepithelial cells in a chondromyxoid field with a capsule with well defined border, Pleomorphic Adenoma. Minor salivary glands are scattered throughout the upper respiratory-digestive system and their number is between 450-1000 and more in the oral cavity [13]. In a study conducted by Tselcos and his colleagues in 2022, the most common pleomorphic site of oral adenoma was diagnosed in the palatal region [14]. There is a difference of opinion in the treatment of pleomorphic adenoma of the palate. Some believe that enucleation with preservation of the upper mucus and some suggest extensive excision. Due to the nature of the capsule, which of course is thick in some patients and thin in some patients and attached to the palatal mucosa or absent [1], wide excision with a safe margin of 1cm is suggested by most surgeons. excision and shaving of the palatal bone in the form of a ostectomy was not needed to reduce the recurrence of the lesion, because the nature of the tumor is not an osteoblast stimulator for bone formation. Keywords: Pleomorphic adenoma; Palatal area; Enuclation.
1- Wu YC, Wang YP, Cheng SJ, Chen HM, Sun A, Chang JY: Clinicopathological study of 74 palatal pleomorphic
adenomas. J Formos Med Assoc. 2016, 115:25-30.
2- Mukul SK, Kumar A, Mokhtar EA, Pandey S: Pleomorphic adenoma of buccal mucosa: an uncommon
presentation among cheek swellings. IP Indian J Anat Surg Head Neck Brain. 2017, 3:48-50
3-Traiger J, Rosen MB. Mixed tumor of the cheek; report of a case. Oral Surg Oral Med Oral Pathol, 1965; 19:711-714.
4-Berdal P, Hall JG. Parapharyngeal growth of parotid tumours. Acta Otolaryngol Suppl, 1969; 263:164-6.
5- Carr RJ, Bowerman JE. A review of tumors of the deep lobe of the parotid salivary gland. Br J Oral Maxillofac Surg, 1986; 24:155-68.
6-Moon SY: Surgical management of the palatal pleomorphic adenoma . J Craniofac Surg. 2019, 30:e580-2.
7- Gao M, Hao Y, Huang MX, et al.: Salivary gland tumours in a northern Chinese population: a 50-year retrospective study of 7190 cases. Int J Oral Maxillofac Surg. 2017, 46:343-9.
8- Chaturvedi M, Jaidev A, Thaddanee R, Khilnani AK: Large pleomorphic adenoma of hard palate . Ann Maxillofac Surg. 2018, 8:124-6.
9- da Silva LP, Serpa MS, Viveiros SK, et al.: Salivary gland tumors in a Brazilian population: a 20-year retrospective and
multicentric study of 2292 cases. J Craniomaxillofac Surg. 2018, 46:2227-33.
10-Hiyama T, Kuno H, Sekiya K, Oda S, Kobayashi T: Imaging of malignant minor salivary gland tumors of the head and neck. Radiographics. 2021, 41:175-91.
11-Berrerhdoche Z, Lachkar A, Benfadil D, Elayoubi F: Pleomorphic adenoma of the palate: a case report . Cureus. 2022, 14:e31003.
12-De Lima FF, Bezerra CP, Rocha AC, Martins IS, Bernaola-Paredes WE: Surgical management of palatal pleomorphic adenoma (PPA) recurrence after 10 years, treated at a Brazilian Center - a case report. Ann Maxillofac Surg. 2020, 10:533-6.
13-Tian Z, Li L, Wang L, Hu Y, Li J: Salivary gland neoplasms in oral and maxillofacial regions: a 23-year retrospective study of 6982 cases in an eastern Chinese population. Int J Oral Maxillofac Surg. 2010, 39:235-42.
14-Antonios Tsekos · Dimitris Tatsis · Anastasia Fotiadou · Nikolaos Kechagias · Konstantinos Vahtsevanos, Pleomorphic Adenoma of Palatal Minor Salivary Glands with Bone
Infiltration: Case Report with Long‑term Follow‑up, Comprehensive Clinical Medicine (2022) 4:215https://doi.org/10.1007/s42399-022-01297-9.
15- Paola Bonavolontà,Department Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University of Naples, Naples, Italy, Giovanni Dell'Aversana Orabona Department Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University of Naples, Naples, Italy, Postoperative complications after removal of pleomorphic adenoma from the parotid gland: A long-term follow up of 297 patients from 2002 to 2016 and a review of publications , British Journal of Oral and Maxillofacial Surgery
Volume 57, Issue 10, December 2019.
16-Eduardo Costa Studart Soares , DDS, MS, PhD/Federal University of Ceará (Professor Titular) and et al, Surgical approach to pleomorphic adenomas arising in the palate: a 10-year retrospective study in a Brazilian population, J Oral Diag [online]. 2016.
17-Babacar Tamba, Mamadou Diatta, Mouhammad Kane, Baidy Lo, Abdou Ba, Soukeye Dia Tine , Oral Surgery Department, Odontology and Stomatology Institute, Cheikh Anta Diop University, Dakar, Senegal , Odontostomatology Department, General Hospital Idrissa Pouy, Dakar, Senegal, Management of a giant pleomorphic adenoma of the palate: Case report , Advances in Oral and Maxillofacial Surgery,2021
adenomas. J Formos Med Assoc. 2016, 115:25-30.
2- Mukul SK, Kumar A, Mokhtar EA, Pandey S: Pleomorphic adenoma of buccal mucosa: an uncommon
presentation among cheek swellings. IP Indian J Anat Surg Head Neck Brain. 2017, 3:48-50
3-Traiger J, Rosen MB. Mixed tumor of the cheek; report of a case. Oral Surg Oral Med Oral Pathol, 1965; 19:711-714.
4-Berdal P, Hall JG. Parapharyngeal growth of parotid tumours. Acta Otolaryngol Suppl, 1969; 263:164-6.
5- Carr RJ, Bowerman JE. A review of tumors of the deep lobe of the parotid salivary gland. Br J Oral Maxillofac Surg, 1986; 24:155-68.
6-Moon SY: Surgical management of the palatal pleomorphic adenoma . J Craniofac Surg. 2019, 30:e580-2.
7- Gao M, Hao Y, Huang MX, et al.: Salivary gland tumours in a northern Chinese population: a 50-year retrospective study of 7190 cases. Int J Oral Maxillofac Surg. 2017, 46:343-9.
8- Chaturvedi M, Jaidev A, Thaddanee R, Khilnani AK: Large pleomorphic adenoma of hard palate . Ann Maxillofac Surg. 2018, 8:124-6.
9- da Silva LP, Serpa MS, Viveiros SK, et al.: Salivary gland tumors in a Brazilian population: a 20-year retrospective and
multicentric study of 2292 cases. J Craniomaxillofac Surg. 2018, 46:2227-33.
10-Hiyama T, Kuno H, Sekiya K, Oda S, Kobayashi T: Imaging of malignant minor salivary gland tumors of the head and neck. Radiographics. 2021, 41:175-91.
11-Berrerhdoche Z, Lachkar A, Benfadil D, Elayoubi F: Pleomorphic adenoma of the palate: a case report . Cureus. 2022, 14:e31003.
12-De Lima FF, Bezerra CP, Rocha AC, Martins IS, Bernaola-Paredes WE: Surgical management of palatal pleomorphic adenoma (PPA) recurrence after 10 years, treated at a Brazilian Center - a case report. Ann Maxillofac Surg. 2020, 10:533-6.
13-Tian Z, Li L, Wang L, Hu Y, Li J: Salivary gland neoplasms in oral and maxillofacial regions: a 23-year retrospective study of 6982 cases in an eastern Chinese population. Int J Oral Maxillofac Surg. 2010, 39:235-42.
14-Antonios Tsekos · Dimitris Tatsis · Anastasia Fotiadou · Nikolaos Kechagias · Konstantinos Vahtsevanos, Pleomorphic Adenoma of Palatal Minor Salivary Glands with Bone
Infiltration: Case Report with Long‑term Follow‑up, Comprehensive Clinical Medicine (2022) 4:215https://doi.org/10.1007/s42399-022-01297-9.
15- Paola Bonavolontà,Department Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University of Naples, Naples, Italy, Giovanni Dell'Aversana Orabona Department Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University of Naples, Naples, Italy, Postoperative complications after removal of pleomorphic adenoma from the parotid gland: A long-term follow up of 297 patients from 2002 to 2016 and a review of publications , British Journal of Oral and Maxillofacial Surgery
Volume 57, Issue 10, December 2019.
16-Eduardo Costa Studart Soares , DDS, MS, PhD/Federal University of Ceará (Professor Titular) and et al, Surgical approach to pleomorphic adenomas arising in the palate: a 10-year retrospective study in a Brazilian population, J Oral Diag [online]. 2016.
17-Babacar Tamba, Mamadou Diatta, Mouhammad Kane, Baidy Lo, Abdou Ba, Soukeye Dia Tine , Oral Surgery Department, Odontology and Stomatology Institute, Cheikh Anta Diop University, Dakar, Senegal , Odontostomatology Department, General Hospital Idrissa Pouy, Dakar, Senegal, Management of a giant pleomorphic adenoma of the palate: Case report , Advances in Oral and Maxillofacial Surgery,2021
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Issue | Vol 11, No 3 (Summer 2024) | |
Section | Case Report(s) | |
Keywords | ||
Pleomorphic adenoma; Palatal area; Enuclation. |
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How to Cite
1.
Sharifi Rayeni A, Yeganeh A. Pleomorphic Adenoma in Palatal Region of a Young Patient: A Case Report. J Craniomaxillofac Res. 2024;11(3):190-194.