Case Report

Mural Unicystic Ameloblastoma in Anterior Region of Mandible: A Case Report

Abstract

Ameloblastoma is a benign but locally invasive epithelial odontogenic tumor. Ameloblastoma usually presents in the posterior mandibular ramus region, while it is rare in the anterior mandibular region. It has been divided into three classic types: Unicystic Ameloblastoma (UA), Extraosseous/Peripheral Ameloblastoma, and Conventional Ameloblastoma. The unicystic type accounts for approximately 5-15% of all cases and predominantly occurs in the younger population, typically in the second decade of their life, but is quite rare in older adults. We present a case of mandibular unicystic Ameloblastoma in the anterior area of a 62-year-old Iranian female with intraoral swelling of the gingiva. We reported the clinicoradiographic and histopathological features of the lesion with complete treatment intervention and follow-up. Keywords: Ameloblastoma; Mural; Odontogenic tumor. 
1. Ramesh RS, Manjunath S, Ustad TH, Pais S, Shivakumar K. Unicystic Ameloblastoma of the mandible--an unusual case report and review of literature. Head Neck Oncol. 2010;2:1.
2. Agani Z, Hamiti-Krasniqi V, Recica J, Loxha MP, Kurshumliu F, Rexhepi A. Maxillary unicystic Ameloblastoma: a case report. BMC Res Notes. 2016;9(1):469.
3. Chae MP, Smoll NR, Hunter-Smith DJ, Rozen WM. Establishing the natural history and growth rate of Ameloblastoma with implications for management: systematic review and meta-analysis. PLoS One. 2015;10(2):e0117241.
4. Soluk-Tekkesin M, Wright JM. The World Health Organization Classification of Odontogenic Lesions: A Summary of the Changes of the 2022 (5th) Edition. Turk Patoloji Derg. 2022;38(2):168-84.
5. Hirschhorn AI, Vered M, Buchner A, Greenberg G, Yahalom R. Unicystic Ameloblastoma in an infant: a management dilemma. J Craniomaxillofac Surg. 2013;41(8):e226-30.
6. Hendra FN, Natsir Kalla DS, Van Cann EM, de Vet HCW, Helder MN, Forouzanfar T. Radical vs conservative treatment of intraosseous Ameloblastoma: Systematic review and meta-analysis. Oral Dis. 2019;25(7):1683-96.
7. Pereira de Castro Lopes SL, Flores IL, de Oliveira Gamba T, Ferreira-Santos RI, Leonelli de Moraes ME, Alvarez Cabello A, et al. Aggressive unicystic Ameloblastoma affecting the posterior mandible: late diagnosis during orthodontic treatment. J Korean Assoc Oral Maxillofac Surg. 2017;43(2):115-9.
8. Giraddi GB, Arora K, Saifi AM. Ameloblastoma: A retrospective analysis of 31 cases. J Oral Biol Craniofac Res. 2017;7(3):206-11.
9. Silva JN, Santos CN, Rocha AC, Carli ML, Hanemann JAC, Pereira AAC. Extensive Ameloblastoma in young patient: 5-year follow-up with no recurrence using conservative treatment. RGO-Revista Gaúcha de Odontologia. 2018;66:181-6.
10. Shankar K, Krishna PS, Rajesh E, Anitha N. Unicystic Ameloblastoma–Cyst or Tumour. Biomedical & Pharmacology Journal. 2015;8(SpecialOct):259.
Files
IssueVol 12, No 1 (Winter 2025) QRcode
SectionCase Report(s)
Keywords
Ameloblastoma; Mural; Odontogenic tumor.

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How to Cite
1.
Derakhshan S, Moradzadeh Khiavi M, Parnia Baran Z. Mural Unicystic Ameloblastoma in Anterior Region of Mandible: A Case Report. J Craniomaxillofac Res. 2025;12(1):61-65.